People with this condition cannot break down the sugars sucrose and maltose, and other compounds made from simple sugar molecules carbohydrateswhich can cause diarrhea, abdominal pain, and other symptoms.
Pepsin: Signs You Need More of This Digestive Enzyme & How to Get It in Your Diet
Sucrose a sugar found in fruits, and also known as table sugar and maltose the sugar found in grains are called disaccharides because they are made of two simple sugars.
Disaccharides are broken down into simple sugars during digestion. Sucrose is broken down into glucose and another simple sugar called fructose, and maltose is broken down into two glucose molecules. Other names for CSID include genetic sucrase-isomaltase deficiency GSIDcongenital sucrose intolerance, congenital sucrose-isomaltose malabsorption, disaccharide intolerance I, SI deficiency, or sucrase-isomaltase deficiency.
Congenital sucrase-isomaltase deficiency usually becomes apparent after an infant is weaned and starts to consume fruits, juices, and grains and often is diagnosed under the age of 18 months.
It may sometimes be diagnosed in older children or adults, however the frequency of CSID in adults has not yet been determined. After ingestion of sucrose or maltose, an affected person will typically experience watery diarrhea, bloating, excess gas production, abdominal pain "stomach ache"and malabsorption of other nutrients.
Other symptoms may include nausea, vomiting, or reflux-like symptoms. In some children, these digestive problems can lead to failure to gain weight and grow at the expected rate failure to thrive and malnutrition. Most affected children are better able to tolerate sucrose and maltose as they get older. Symptoms can vary for a variety of reasons including the timing of introduction of sucrose into a person's diet, and the amount of sugar and starch consumed.
Infants who are breast-fed or fed lactose-containing formula will often not have symptoms of CSID until they ingest juices, solid foods, or medications that are sweetened by sucrose.
Holistic Primary Care
In some people symptoms may be milder than typically expected. Those with milder symptoms may not be diagnosed until later in childhood or in adulthood.
The prevalence of CSID is still unknown and a subject of study and debate. Estimates of prevalence in people of European descent generally range from 1 in to 1 in 2, and fewer African Americans are thought to be affected. The condition is much more prevalent in the indigenous populations of Greenland, Alaska, and Canada, where as many as 1 in 10 to 1 in 30 people may be affected.
Nevertheless, more recent studies suggest that CSID may be more common than currently estimated. It is possible that some people remain undiagnosed and that the incidence is higher. Mutations in a gene the SI gene cause congenital sucrase-isomaltase deficiency. The SI gene provides instructions for producing the enzyme sucrase-isomaltase.
This enzyme is found in the small intestine and is involved in the digestion of sugar and starch. It is responsible for breaking down sucrose and maltose into their simple sugar components.
These simple sugars are then absorbed by the small intestine. In addition to genetic variations, other factors including dietary, gut motility, and nutritional interactions can affect the severity of symptoms. The standard method of confirming a diagnosis of suspected CSID is with an endoscopic biopsy, a tissue sample, taken from the small intestine for laboratory analysis.All dairy products contain called a sugar molecule known as lactose. It is composed of two smaller sugar molecules, glucose and galactose.
Choosing Your Foods
To absorb lactose into our bodies, our small intestines must break it back down into those smaller molecules. The enzyme lactase breaks down these lactose molecules that we consume from dairy products.
It makes the absorption process easier and much more efficient to utilize. Lactose intolerance is a common condition in which the body does not produce enough lactase enzymes to break down and absorb lactose molecules.
This can result in diarrhea, gas, bloating, abdominal discomfort, and pain. The absence of lactase typically begins to occur after childhood or can be a result from a disease that affects the small intestines.
To address this issue, people take a lactase enzyme supplement when they consume some sort of dairy food. These supplements provide the lactase enzymes that are not present in the body and assist with the breaking down of lactose. As a result, it relieves them of the aforementioned side effects and effectively digests the lactose.
Lactase supplements are not only for those with lactose intolerance. There are some people who can digest dairy products more easily than others but still get a little bloated or have gas. Lactase supplements can help alleviate these issues. Lactase Powder is designed to provide efficient amounts of lactase enzymes to help with the breakdown of lactose molecules for those with lactose intolerance, causing a relief of gas, bloating, diarrhea, and digestive discomfort. Lactaid Fast Act Lactose Intolerance Relief Pills are naturally-designed to work and make dairy foods easier to digest.
It is perfect for those with lactose intolerance. Its fast-acting formula helps prevent gastrointestinal issues when consuming dairy products. Lactase enzymes break down lactose molecules that come from dairy products.
They reduce bloating, diarrhea, and gas that occur when lactose is not sufficiently broken down. Lactaid Fast Act Relief Pills are easy to swallow and are suitable for ages 4 and up.There are many important enzymes but the enzymes that help break down complicated sugars into simple sugars are increasingly important in a ruled by sweet food world. Sucrase enzymes digest complex sugars and starches into simple sugars like glucose and fructose. Ultimately the main job in the naturally occurring sucrase is the breakdown of foods that allows the absorption of healthy nutrients.
Even in complicated sugar foods the breaking down of those sugars into sugars the body can use for energy or other sources is vital in maintain a healthy body and a healthy digestive system. The other benefits to sucrase enzymes are the fact that they can help eliminate viruses and break down damaged tissues. These processes increase the growth of tissue and reduce inflammation. Enzymes in general are needed for our systems balance and absorption of healthy nutrients to fend of various illnesses and bacteria.
The benefits of sucrase enzymes come from the chemical reaction with sucrose which ends up producing glucose and fructose. Glucose and fructose are absorbed much easier and once absorbed into the system give humans a boost of energy. For those who feel the effects of a sucrase deficiency in the form of digestive issues, there are natural ways of supplementing sucrase to the system.
The side effects could include acid reflux, bloating and indigestion. Supplementation of sucrase has many benefits to human body but mainly it helps boost energy levels and keeps digestion running smoothly in our bodies. With lower levels of sucrase people will notice their energy levels dipping during the day. Sugar is a difficult food to say no to completely and it is even needed for the body to be healthy. Sucrase is important to our health because the breakdown of sugars is one of the more vital things that need to happen for maintaining our health.
If you decide to supplement your body with certain enzymes, it is very important to choose a product that has very pure ingredients and will show results. Take a look at our top ranked digestive enzyme blend and see how it can help your digestive issues.
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This product is not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, have a serious medical condition, or have a history of heart conditions we suggest consulting with a physician before using any supplement.People with CSID may need to work with their physician and a registered dietitian to develop an individualized diet plan to meet their specific needs.
In general, dietary treatment, when necessary, may need to be combined with therapeutic treatment to focus on restricting the consumption of sugar sucrose and starch isomaltose and maltose.
The degree of restriction an affected individual needs is specific to each person. Keeping food logs or food diaries is an important part of dietary planning for individuals affected by CSID.
All foods and beverages consumed should be recorded. Symptoms, such as bloating, gas, diarrhea, or abdominal pain, should also be recorded. The time of symptom onset and the duration of the symptoms should be recorded as well.
A food and symptom log helps you and your registered dietitian identify trigger foods, and thus is an aid in developing an appropriate diet that meets your specific needs.
Therefore, it should not be followed for more than approximately two weeks without close guidance from a physician or registered dietitian. The elimination diet has two phases: a sugar elimination phase and a starch elimination phase. Sucrose, known as table sugar or white sugar, is a carbohydrate that is added to many processed foods.
Sucrose also occurs naturally in some foods, such as fruits and juices. People with CSID who are not being treated have trouble digesting foods containing sucrose. After the initial two-week elimination diet is completed, sucrose-containing foods are gradually reintroduced into the diet to determine how much sucrose can be tolerated. It is recommended that only one new food be reintroduced into the diet every three to five days before adding the next new food.
Symptoms should be closely monitored during this time to help identify foods that trigger symptoms. Starch, in addition to fiber and sugars, is another type of carbohydrate. Starch is found in grains like wheat, oats, rice, and starchy vegetables like corn, potatoes, beans, peas, and lentils. Breads, cereals, and crackers, including gluten-free breads and crackers, are all foods with a high starch content. Other sources of starch include certain additives such as maltodextrin, a modified tapioca starch.
After the two-week elimination period, it is important to determine starch tolerance by re-introducing starch-containing foods gradually one new food every three to five days. It is also important to continue recording your food intake and symptoms during this time.
If available, disaccharidase assay results a test that determines how much enzyme activity exists in the small intestine may be used as an initial indication of general starch tolerance.
Below is a table to assist people with CSID, physicians, and registered dietitians in planning both the elimination diet low-sucrose, low-starch and the reintroduction of foods as your level of sucrose and starch tolerance is established.Seneff believes that sulfate deficiency is a major culprit behind most modern chronic diseases and health conditions.
But it is one that is largely overlooked. Sulfate, comprised of the elements sulfur and oxygen is the fourth most abundant anion in our blood.Starch Intolerance: 5 Reasons You Don't Tolerate Carbs and How To Fix Them
It exists throughout the body in a variety of forms, filling numerous biological functions. A critical component of extracellular matrix proteins, it aids in the detoxification of drugs, food additives, and toxic metals. It also prevents blood from coagulating during transit through capillaries. Cerebroside sulfate, an integral constituent of the myelin sheaths surrounding neuronal axons in the brain, helps to maintain optimal neurological health. Like vitamin D--the widely recognized "sunshine vitamin"--sulfate levels depend depend on sun exposure.
It is synthesized from sulfide in the skin and red blood cells via a sunlight-dependent chemical reaction. Seneff described the skin as "a solar powered battery" that captures energy from sunshine to catalyze sulfate synthesis. In her research, Seneff identified what she describes as two critical and "mysterious" forms of sulfate: vitamin D3 sulfate and cholesterol sulfate.
We simultaneously produce both molecules, which exist in the bloodstream and many other parts of the body, when we're exposed to sunlight. Vitamin D and cholesterol share a key biochemical connection. Cholesterol, though potentially harmful in large quantities, must be present for the body to make vitamin D.
Sunlight acts like a bridge between the two nutrients, as ultraviolet B rays from the sun reach the skin and activate 7-hydrocholesterol, a chemical precursor of vitamin D, converting it to vitamin D3. While many people get their vitamin D3 from nutritional supplements, Seneff pointed to a significant difference between the type our bodies produce naturally and the kind that comes from a bottle. In the presence of sunlight, skin cells produce vitamin D3 sulfate, a water-soluble form of the typically fat-soluble vitamin D.
The sulfate form can travel freely throughout the bloodstream. J Pharmacol Pharmacother. Sun exposure is really the key. In addition to vitamin D, many other vitamins, hormones, and neurotransmitters must be sulfated for transport in the blood.
Sulfate transport, says Seneff, ranks among the most important bodily functions these various substances perform. Mysterious Molecules.
Cholesterol sulfate is another mystery molecule that Seneff believes deserves more attention from health practitioners.Some individuals have found dietary supplements to be helpful in reducing the gastrointestinal symptoms associated with isomaltase deficiency. Therefore, they have looked into supplements for this purpose.
Digestive Enzyme Supplements: Splitting Fact From Fiction
It should be noted that dietary supplements differ from prescription medication in several important ways. First, dietary supplements are not FDA-approved. This means that they are not subject to the same standards of rigor or manufacturing quality control as prescription medications. Secondly, there are vast potency differences between dietary supplements and prescription medications.
Finally, enzymes are proteins and are subject to degradation. Most dietary enzyme supplements are not dispensed in refrigerated packages. As a result, the enzymes contained in these supplements may not survive the packaging and shipping process intact. Before taking a dietary supplement, you should discuss it with your physician.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www. About CSID. If you notice any swelling or have difficulty breathing, get emergency help right away. Tell your doctor if you are allergic to, have ever had a reaction to, or have ever had difficulty taking yeast, yeast products, papain, or glycerin glycerol. You may need to restrict the amount of starch in your diet. Your doctor will tell you if you should restrict starch in your diet.
Your doctor will tell you if your diet or diabetes medicines need to be changed. Check with your doctor if you notice these or other side effects.Pepsin is considered one of the main digestive enzymes that humans and many other animals produce. In addition, it helps with functions like nutrient absorption and protection against allergies, yeast overgrowth and more. Today pepsin supplements are available that can aid in digestion when low levels of this enzyme are produced.
It can help curb indigestion and symptoms associated with pancreatitis, GERD, acid reflux and heartburn. Do you suspect that you might have low stomach acid? It can contribute to problems digesting protein. Symptoms like abdominal pain, bloating, diarrhea, and nutrient deficiencies in B12 and iron may all indicate that you lack adequate gastric juices and pepsin. Pepsin is an enzyme made by the stomach.
It also functions in the stomach. This enzyme is created when stomach acid changes a protein called pepsinogen into pepsin. Pepsin can be found in gastric juices that are acidic and needed to properly metabolize the foods we eat. Glands in the mucous-membrane lining of the stomach, called peptic chief cells, are responsible for making pepsinogen. This happens after they are stimulated by the vagus nerve and hormonal secretions of gastrin and secretin.
Pepsinogen mixes with hydrochloric acid and is then converted to the active enzyme pepsin. Pepsin has maximal activity in acidic environments, ideally around a pH of about 1. It then causes pepsin to be neutralized and denatured. This is important because inside the stomach is intended to be an acidic place. Once pepsin degrades proteins into smaller peptides, peptides are then absorbed from the intestine into the bloodstream or further broken down by pancreatic enzymes.
Some pepsin is capable of passing from the stomach into the bloodstream, where it continues to breaks down undigested fragments of protein. This is also believed to help keep the stomach free of most bacteria. How does pepsin work in the body?
Its main function is to break down or denature proteins, but it also has other roles, including facilitating nutrient absorption and killing harmful microbes. The role of digestive enzymes is primarily to act as catalyst in chemical reactions in the body.
Digestive enzymes turn larger molecules into more easily absorbed particles that the body can actually use to survive and thrive. There are several main reasons why some people can benefit from taking pepsin enzymes. Pepsin benefits and uses include:. Although pepsin is an important digestive enzyme with many benefits, there are several digestive problems that are linked to dysfunction of pepsin. These include:.
Foods in your diet do not actually contain pepsin, but they can affect your production of stomach acid and digestive enzymes. The volume you produce increases if you eat high volumes of protein. Pepsin medications and supplements are also sources of pepsin. These are used to enhance digestion of food especially proteins when someone lacks proper pepsin secretion.
Pepsin supplements are usually produced from hog or swine pig stomachs. The product called betaine hydrochloride or betaine HCL with pepsin is recommended by some practitioners a supplemental source of hydrochloric acid for people who have low stomach acid production also called hypochlorhydria.
This may help hydrochloric acid secreted by the stomach better convert pepsinogen and aid in digestion of protein. Pepsin supplements include drugs that are available as over-the-counter pills that can be taken without a medical prescription. They are available in the form of tablets, compounding powders and capsules.